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What does neuroimaging tell us about visual coding strategies?

Dae-Shik Kim

 


Cognitive neuroimaging based on functional magnetic resonance imaging (fMRI) provides important information about networks of co-activated areas, thus yielding information about the "where" of the brain's information processing. What is the significance, however, of such localization data for the understanding of the spatial coding strategies used by the brain? We performed three studies to link fMRI in animal and human visual cortices in greater detail with existing body of visual neuroscience data. In the first, "Head-From-Motion" experiment, we could map the detailed, intra-areal spatial structure of human ventral visual areas with respect to different perceived object categories induced by almost identical physical stimuli. In the second experiment in animals, we were able to elucidate the spatial extent to which the observed neuroimaging data might correlate with the underlying spiking and subthreshold activities. In the third series of experiment, we obtained diffusion tensor (DTI) based axonal connectivity pattern in vivo in combination with functional neuroimaging data. The results of our studies suggest that MR imaging at ultra-high fields may provide important insights into the visual coding strategies in vivo.